CRP and anemia: A couple of recent papers also proposed a grading system: (1) incorporating the independent prognostic significance of both BMI and percentage of weight loss (Martin et al., 2015) or (2) according to changes on biochemistry (high C-reactive protein or leukocytes, or hypoalbuminemia, or anemia), food intake, weight loss, and performance status (Vigano et al., 2016).