G6PD and Hyperglycemia: Curcumin may prevent alterations of protein carbonyls, antioxidant enzymes glutathione peroxidase (GPx), glucose-6-phosphate dehydrogenase (G6PD) and significantly decreased GSH levels, demonstrating curcumin delay the progression of diabetic cataract by preventing hyperglycemia-mediated lenticular oxidative stress in rats (Suryanarayana et al., 2005).