Transferrin (Tf) is a glycoprotein used to improve targeting efficiency for the tumor cells which overexpress the Tf-receptor by grafting to nanoparticles made of poly(L-lysine) (Wagner et al., 1990), polyethyleneimine (Ogris et al., 2003), cyclodextrin (Bellocq et al., 2003), or polyamidoamine (Huang et al., 2007). This evidence concerns the gene TF and neoplasm.