MKI67 and bone metastasis: On multivariate Cox analysis, 6PGL positivity (hazard ratio [HR] 4.180; 95% confidential interval [CI] 1.160–15.06; p = 0.029) and lower Ki-67 LI (HR 11.853; 95% CI 1.841–76.30; p = 0.009) were independent risk factors for shorter overall survival in bone metastasis and lung metastasis, respectively (Table 5).