LMO1 and acute lymphoblastic leukemia: Similarly, even though GATA3 is highly expressed in T-ALL cells,12 the GATA3 binding site in the first intron of LMO1, which mediates super-enhancer formation in neuroblastoma,34 is not bound by GATA3 in T-ALL cells (compare Figure 5a with 3a in Oldridge et al.34).