The expression of macrophage markers (CD14 and MAC-1), neutrophils (Ly6G), monocyte chemoattractant protein (MCP-1), angiogenesis marker (VEGF) and matrix metalloproteases (MMP-1 and MMP-2) were also upregulated in retinal degeneration models CBA/J and NOD.SCID-rd1. The gene discussed is CCL2; the disease is retinal degeneration.