For example, mutations in SLX4 (FANCP) and XPF (FANCQ) are associated with Fanconi anemia (FA) (Bogliolo et al., 2013, Kashiyama et al., 2013, Kim et al., 2011, Stoepker et al., 2011), a rare autosomal recessive disorder characterized by physical abnormalities, bone marrow failure, and cancer predisposition. This evidence concerns the gene SLX4 and Bone marrow hypocellularity.