TIA1 and colorectal carcinoma: Moreover, compared with cells transfected with miR-19a mimic alone, those transfected with both the miR-19a mimic and TIA1 overexpression plasmid exhibited a significantly lower migration rate (Fig. 6a and c), suggesting that miR-19a-resistant TIA1 is sufficient to rescue the suppression of TIA1 through miR-19a and attenuate the pro-migration effect of miR-19a on CRC cells.