Interestingly, when our patients were evaluated for their clinical subtypes of JIA, there was a significant positive association between the IL-10 (-1082) AA genotype and susceptibility to polyarticular JIA (OR: 4.3; 95% CI: 1.5–12.7 for the AA genotype; P <0.01); Table 3. The gene discussed is IL10; the disease is polyarticular juvenile idiopathic arthritis.