To validate the prediction that peroxisome pathways involved in lipid metabolism and likely peroxisome biogenesis are increased during latent infection, we examined the protein levels of ABCD3, an ATP Binding Cassette Subfamily D Member 3, a lipid transporter specific to peroxisomes and a common marker to study peroxisomes, using flow cytometry at 48 and 96 hpi (Fig 4A–4H). Here, ABCD3 is linked to disease arising from reactivation of latent virus.