Intestinal damage secondary to murine DSS-induced colitis[9, 10, 31], ischemia/reperfusion injury[16, 17] total body irradiation[24] and infectious colitis[32] are all associated with a robust inflammatory response, and specifically, with robust expression of the inflammatory cytokines, IL1β, IL10, and TNFα. The gene discussed is IL1B; the disease is colitis.