18F-FP-(+)-DTBZ PET imaging can visualise the therapeutic effect of magnolol on the dopaminergic neurons of MPTP-lesioned PD mouse models, while in vivo imaging of striatal VMAT2 distribution using 18F-FP-(+)-DTBZ PET can be a valuable method for monitoring and quantifying the treatment efficacy of neuroprotective agents on PD. The gene discussed is SLC18A2; the disease is Parkinson disease.