XIAP and familial pancreatic carcinoma: With a simultaneous silencing of B-cell lymphoma-extra-large (BCL-XL), C-FLIP, K-RAS, antiapoptotic myeloid cell leukemia-1 (MCL1L), X-linked inhibitor of apoptosis protein (XIAP), and survivin (SUR), they demonstrated both apoptosis induction and proliferation inhibition in pancreatic cancer cells in vitro and in vivo [57].