TNF and infection: Experimental settings of oral candidiasis in immunosuppressed mice showed that oral administration of bLf displayed therapeutic effect by inhibiting the suppressive effects of infection on inflammatory parameters of innate response, such as circulating PMN neutrophils and cervical lymph-node cells; moreover, generation of IFNγ and TNFα was found increased in cervical lymph-nodes cultures primed with heat-killed C. albicans from bLf-treated mice [124].