ITGAM and infection: However, abrogation of monocyte entry into the infected tissue in the CCR2−/− model did not prevent virus dissemination and disease, which indicated that despite moDCs being preferred early EBOV targets, ferrying of infectious viruses by other migratory populations such as conventional CD11b+ DCs, or draining of free virus through the lymphatic system, may be sufficient for viral spread from the infection site to the body.