Furthermore, recent study by Peng et al. 105 also showed that andrographolide inhibited proliferation and invasiveness of NPC HK1 cells via suppressing NF-κB transcriptional activity, thus providing a rational for the possibility of utilizing the NF-κB activation status to stratify NPC patients who may be more likely to benefit therapy with NF-κB inhibitors. The gene discussed is NFKB1; the disease is nasopharyngeal carcinoma.