Since CSF1 is a known macrophage chemoattractant and an interaction between CSF1 and is receptor CSF1R (FMS/CD115) was identified in our microarray data analysis (Fig. 5c), we tested if an anti-CSF1 function-blocking antibody might reduce macrophage migration stimulated by neurofibroma SC conditioned medium. This evidence concerns the gene CSF1 and plexiform neurofibroma.