High Trop2 and high AREG (T+A+), high Trop2 and low AREG (T+A‐), low Trop2 and high AREG (T‐A+), low Trop2 and low AREG (T‐A‐) expression were detected, respectively, in gastric tissues, which including cancer, matched adjacent tissue, chronic gastritis, intestinal metaplasia, intraepithelial neoplasia (Fig. 1). Here, TACSTD2 is linked to chronic gastritis.