METTL21B has been linked to multiple sclerosis 59, 60, 61, mutation of METTL23 has been linked to intellectual disability 62, 63 and METTL21C has been found to be important in muscle cell differentiation and bone cell viability, and thereby is associated with osteoporosis and sarcopenia 64. This evidence concerns the gene METTL23 and multiple sclerosis.