Multivariable logistic regression analysis showed that being single (OR: 2.6, 95 CI: 1.1–6.1, and p = 0.026), current low CD4+ counts of <200/μL (OR: 2.9, 95% CI: 1.1–7.7, and p = 0.031), and UTI symptoms (OR: 2.5, 95% CI: 0.6–8.3, and p = 0.03) were independent predictors of UTI among HIV-positive pregnant women. The gene discussed is CD4; the disease is bacterial urinary tract infection.