IL27 and neuroblastoma: IL-27 has been reported to induce the expression of MHC class-I molecules, a typical effect of IFNs, in different cell types including mouse naïve CD4+ T cells [113], neuroblastoma cells [34], human monocytic cell lines [117], endothelial cells [118], hepatocytes, hepatoma cell lines [119], and hepatic stellate cells [120].