PROM1 and hepatocellular carcinoma: Cell number was measured following treatment with cisplatin, doxorubicin, which can induce ROS accumulation, with or without pretreatment with sulfasalazine in CD133-positive HCC and CD133-negative HCC cells: pretreatment with sulfasalazine dramatically enhanced sensitivity to anticancer drugs in CD133-positive HCC but not CD133-negative HCC (Fig. 5d).