CD14 and HIV-1 infection: To assess whether alterations in cell frequencies during acute HIV-1 infection might impact our results, we compared the frequency of conventional (CD14+CD16-) and inflammatory monocytes (CD14+CD16+) as well as mDCs (CD11c+HLADR+) and pDCs (HLADR+CD123+) in PBMCs from acutely infected subjects and HIV-1 uninfected control subjects.