MTOR and Sepsis: mTOR has a pivotal role in cells survival and inflammation,18 while mTORC1/mTORC2, 2 distinct multiprotein complexes, may play different roles in cellular responsiveness.18 Our data demonstrated that mTORC1/mTORC2 was responsible for mediating BM-MSC-directed inflammatory modulation and anti-apoptosis effects in sepsis.