The apoptosis index (AI), as assessed by TUNLE assay, was significantly lower in the Raptor KO-sepsis+BM-MSCs group compared with the WT-sepsis+BM-MSCs group (P<0.05) and the WT-sepsis+Raptor overexpression group (P<0.05; Figures 5a and b). This evidence concerns the gene RPTOR and Sepsis.