mTORC1 contains the distinct partner protein (for example, regulatory-associated protein of mTOR Raptor), which are proven to orchestrate various cues including inflammation, survival and apoptosis.18,19 Several studies showed that mTOR was involved in LPS-induced proinflammation cytokines production in dendritic cells.20,21 Therefore, we designed the present study to explore the in vivo crosslink between cardiomyocytes and mTOR in the setting of sepsis and MSC therapy. The gene discussed is RPTOR; the disease is Sepsis.