The above in vitro findings demonstrate a significantly altered phenotype of BMDM from properdin deficient mice in response to tumour cell conditioned medium compared to wildtype mice (skewed towards high IL‐10 protein, high MCP‐1 mRNA, high arginase‐1 mRNA, low Il‐1β mRNA, M2 surface marker profile). Here, CCL2 is linked to neoplasm.