To assess the role of CD8 T cells in driving anti‐tumor immunity in the absence of Treg, tumor bearing BALB/c FoxP3.dtr mice were left untreated (PBS), or treated with CD4 or CD8 depleting antibodies, alone or in combination, in the context of DTX‐mediated Treg depletion (Fig. 4). This evidence concerns the gene CD8A and neoplasm.