TGM2 and celiac disease: In this work we aimed to take advantage of the molecular mechanisms for the initiation of celiac disease by identifying a compound to be used as a potential flour additive that interacts with TG2 binding motives in gluten-derived peptides to inhibit the recognition by TG2 and thus prevent its binding and thereby decrease the formation of the thioester-deamidated gluten peptide that is associated with T-cell activation in celiacs.