CFTR and cystic fibrosis: In a few words, 2DE allowed for the observation of a change in silver stain intensity of 20 (out of 194) spots of cultured CF lung epithelial cells (IB3-1) in comparison with daughter cells repaired by gene transfer with wild-type cystic fibrosis transmembrane conductance regulator (CFTR) (IB3-1/S9).