In other cancers LIN28Bcan be induced by oncogenic drivers that are activated in CRC – byNFΚB (Iliopoulos et al.,2009) and Wnt signaling (Cai et al.,2013) in breast cancer and by MYC in a B-cell lymphoma cell line (Chang et al., 2009) – althoughdirect relevance to CRC remains to be determined. This evidence concerns the gene MYC and colorectal carcinoma.