ASCL2 and colorectal carcinoma: MiR-200 is alsoregulated by the transcription factor ASCL2, which transactivates the miR-200b-a-429promoter (Tian et al., 2014).ASCL2 is a Wnt target gene that promotes stem cell fate in theintestine (van der Flier et al.,2009; Schuijers et al.,2015) and is upregulated in CRC (Jubb et al., 2006).