ADAR and epilepsy: Similarly, ADAR and ADARB1, key enzymes for facilitating A-to-I editing, are significantly differentially expressed as well as highly expressed in both cases and controls [Adar: mean FPKM value = 70, log2 (fold change) = −0.19, P-value = 1 × 10−10; Adarb1: mean FPKM value = 1417, log2 (fold change epilepsy/control) = −0.22, P-value = 8 × 10−13].