AKT1 and hereditary clear cell renal cell carcinoma: The 7 identified miRNAs might be involved in several pathways, including T2DM, renal cell carcinoma, AMPK signaling pathway, and PI3K-Akt signaling pathway; however, the detailed function associated with these miRNAs in AOE therapy needs further investigation and the target genes of miRNAs need further validation through additional studies.