Specifically, NEFH, hepatitis A virus cellular receptor 1 (HAVCR1, 5q33.2), interferon, alpha-inducible protein 27 (IFI27, 14q32), PCSK5, and the arylsulfatase D gene (ARSD, Xp22.3) have been implicated in a variety of cancers. This evidence concerns the gene PCSK5 and cancer.