Kaplan-Meier analysis was performed which confirmed SRF negative correlation from date of diagnosis with prostate cancer (Fig. 3a[ii]; Log-rank test, P = 0.003), castration resistance/ biochemical recurrence (Fig. 3b[ii]; Log-rank test, P = 0.00002), and bone metastases (Fig. 3C[ii]; Log-rank test, P = 0.0044). This evidence concerns the gene SRF and prostate carcinoma.