Nevertheless, statistically significant up-regulation of Interferon-gamma and Interleukin-6 inflammatory cytokines was previously revealed in the blood of patients undergoing IMRT because of prostate cancer, while levels of Interleukin-1 and Interleukin-2 correlated with the risk of radiation toxicity in the analyzed group of 42 patients [30]. This evidence concerns the gene IL6 and Familial prostate cancer.