Target gene predictions for miR-184 and miR-490-5p and the pathway analysis of the target genes of these 2 small RNAs showed that potential target genes of miR-184 were involved in some pathways that were closely associated with UC, such as the TNF signaling pathway, Ras signaling pathway, pathway in cancer, NF-κB signaling pathway, miRNAs in cancer, colorectal cancer, and AMPK signaling pathway. The gene discussed is NFKB1; the disease is colorectal cancer.