To investigate the effect of PKC β inhibitor on the cisplatin-induced autophagy in cervical cancer cells, Hela cells were treated with 0 or 50 μM cisplatin in combination with 0, 1 or 3 μM enzastaurin for 24 h, then the apoptosis of Hela cells were assayed by flow cytometry with Annexin V-FITC Apoptosis Detection Kit. This evidence concerns the gene ANXA5 and cervical cancer.