Interestingly, mouse mutants for the histone N-lysine demethylase Kdm3a (Jmjd1a, Tsga, or Jhdm2a) are obese, predisposed to diabetes (Inagaki et al., 2009; Tateishi et al., 2009), and have male infertility phenotypes (Okada et al., 2007) overlapping with mouse models of dysfunctional cilia. This evidence concerns the gene KDM3A and diabetes mellitus.