PINK1 and idiopathic pulmonary fibrosis: Type II AECs in the lungs of patients with IPF showed defective mitophagy and dysfunctional mitochondria with low expressions of PTEN-induced putative kinase 1 (PINK1) that is thought to have an important role in the maintenance of mitochondrial homeostasis and selective degradation of damaged mitochondria by mitophagy [114].