Only a single small study in 22 non-CKD patients with hyperkalemia after the administration of a high-concentration K+ solution to perform continuous warm-blood cardioplegia reported a higher efficacy (-1.78 mmol/l K+) using a very high amount of glucose (100 g) and an even higher insulin bolus (50 U) [30]. The gene discussed is INS; the disease is Hyperkalemia.