PKD2 and autosomal dominant polycystic kidney disease: Although we recently generated Pkd2 conditional‐knockout mice (Pkd2f3/f3) 27, we still needed to find an appropriate Cre‐recombination system by which the Pkd2f3/f3 model could be used to represent the clinical manifestations of human ADPKD and to assess the effect of various therapeutic interventions.