RPS6KB1 and neoplasm: In this initial study, out of ten putative candidates, three proteins are reliably phosphorylated by AS‐S6K1: Cux1 is a transcription factor involved in tumour suppression and the retrograde control of insulin signalling (Wong et al, 2014); lamin A is a component of the nuclear envelope that may affect ageing (Ghosh & Zhou, 2014); and ZRF1, whose phosphorylation has been more thoroughly characterized here.