PCa patients with high pre-operative PSA (for Taylor: P = 0.003) and Gleason score (for Taylor and TCGA: P = 0.010 and 0.001, respectively), advanced clinical (for Taylor: P = 0.007) and pathological stages (for Taylor: P = 0.004), and positive metastasis (for Taylor: P = 0.001) and biochemical recurrence (BCR, for Taylor and TCGA: P = 0.002 and 0.037, respectively) more frequently had higher expression level of miR-30d than those in the corresponding control groups (Additional file 3: Table S3). Here, KLK3 is linked to posterior cortical atrophy.