SLC5A2 and cardiovascular disorder: Results from the ongoing CANagliflozin cardioVascular Assessment Study (CANVAS; ClinicalTrials.gov Identifier: NCT01032629 [37]) and CANVAS-R (renal endpoints; NCT01989754 [38]) trials in patients with a history or high risk for cardiovascular disease are expected in 2017 and will help determine whether the improvements in cardiovascular outcomes seen with empagliflozin are representative of the SGLT2 inhibitor class.