EZH2 and primary biliary cholangitis: In the univariate analysis, compared with low EZH2 expression, high EZH2 expression was not a poor prognostic indicator of OS after recurrence outcome in PBC (hazard ratio [HR] 1.449; 95% confidence interval [CI] 0.930–2.258, P = 0.101) (Table 5), whereas in metastatic lesions, high EZH2 expression was a poor prognostic indicator of OS outcome after recurrence (HR 2.116; 95% CI 1.143–3.916, P = 0.017) (Table 5).