One of the key players in HR is the partner and localizer of breast cancer susceptibility protein 2 (PALB2), which is mutated in a subset of breast cancer and Fanconi Anaemia patients (FANCN) (Xia et al., 2006; Reid et al., 2007; Antoniou et al., 2014). This evidence concerns the gene PALB2 and Fanconi anemia.