Exacerbated MCMV-induced weight loss in Ifitm3–/– mice was accompanied by a statistically significant higher viral load from day 4 p.i. in the spleen (Figure 1C) and lungs (Figure 1D), but not the liver (Figure 1E), after infection with standard inoculum (3 × 104 PFU). This evidence concerns the gene IFITM3 and infection.