SELE and endothelial dysfunction: Other markers of endothelial dysfunction, such as asymmetric dimethylarginine (ADMA), L-arginine, soluble vascular adhesion molecule-1 (sVCAM-1) and soluble E-selectin (sE-selectin) have also been associated with CKD31, demonstrating that endothelial dysfunction contributes to cardiovascular morbidity/mortality in CKD patients.