Remarkably, we did not observe a significant survival association with other well-known cancer genes, such as PIK3CA (lowest p = 0.007, q = 0.5 in UCEC), BRAF (lowest p = 0.028, q = 0.98 in KIRP), and FBXW7 (lowest p = 0.018, q = 0.99 in MELA-AU). The gene discussed is PIK3CA; the disease is cancer.