Polymorphisms in several genes, including the vitamin D receptor (VDR) gene, the androgen receptor (AR) gene, the cytochrome P-450 17 alpha-hydroxylase/C(17, 20)-lyase (CYP17) gene, and the steroid 5 alpha-reductase type 2 (SRD5A2) gene, have been implicated in PCa development (Wang et al., 2016; Dianat et al., 2009, Ntais et al., 2003). This evidence concerns the gene SRD5A2 and posterior cortical atrophy.