Li et al. (2017) observed that the expression of TGF-β1 and MMP-7 are upregulated in STZ-induced diabetic nephropathy rats but markedly decreased in diabetic nephropathy rats treated with sodium hydrosulfide (Li et al., 2017), which suggests regulation between TGF-β and MMP-7. The gene discussed is TGFB1; the disease is diabetic kidney disease.